TRILAVIR MINI Tablet is a fixed-dose combination antiretroviral medication used for the treatment of HIV-1 infection. It contains three active ingredients: Tenofovir disoproxil fumarate (TDF), Lamivudine (3TC), and Efavirenz (EFV). This combination works to suppress the replication of HIV in the body, helping to reduce the viral load and prevent the progression to AIDS, while improving immune function.
The mini tablet formulation provides a smaller, more easily swallowable tablet option, particularly useful for individuals who may have difficulty taking regular-sized tablets. TRILAVIR MINI is typically prescribed as part of combination therapy, along with other antiretroviral agents, to ensure maximum efficacy in managing HIV.
Key Features
- Active Ingredients:
- Tenofovir disoproxil fumarate (TDF) – 300 mg
- Lamivudine (3TC) – 150 mg
- Efavirenz (EFV) – 200 mg
- Formulation: Small, easy-to-swallow mini tablet
- Indications:
- Treatment of HIV-1 infection in adults and adolescents as part of a combination regimen.
How TRILAVIR MINI Tablet Works
TRILAVIR MINI combines the actions of three drugs to inhibit HIV replication:
- Tenofovir disoproxil fumarate (TDF) and Lamivudine (3TC) are nucleoside reverse transcriptase inhibitors (NRTIs) that block the HIV reverse transcriptase enzyme, preventing the virus from replicating.
- Efavirenz (EFV) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that targets the reverse transcriptase enzyme through a different mechanism, effectively blocking viral replication.
Together, these medications help lower the viral load in HIV-positive individuals and improve the body's immune function, contributing to better overall health.
Dosage and Administration
- HIV Treatment: Take 1 TRILAVIR MINI tablet daily as directed by your healthcare provider, ideally at the same time each day.
- Can be taken with or without food.
- Ensure adherence to the prescribed dosage for the most effective treatment results.
Benefits of TRILAVIR MINI Tablet
- Smaller Size: The mini tablet formulation is easier to swallow for individuals who have difficulty with larger tablets.
- Effective HIV Management: Helps reduce viral load and prevent the progression of HIV infection.
- Convenient Once-Daily Dosing: One tablet per day simplifies the treatment regimen and helps improve adherence.
Common Side Effects
- Nausea
- Dizziness
- Fatigue
- Headache
- Diarrhea
Serious side effects (although rare) include:
- Liver and kidney problems
- Severe skin reactions
- Central nervous system effects (such as mood changes, dizziness, and sleep disturbances from Efavirenz)
Precautions
- Liver and Kidney Function: Regular monitoring is recommended as TRILAVIR MINI can affect liver and kidney health.
- Psychiatric Effects: Efavirenz can cause mood swings, anxiety, and sleep disturbances.
- Pregnancy: Efavirenz should generally be avoided in the first trimester of pregnancy. Consult your healthcare provider for alternatives if pregnant.
- Drug Interactions: Inform your doctor about any other medications you are taking, as TRILAVIR MINI may interact with certain drugs.
Storage Instructions
- Store at room temperature (20–25°C), away from moisture and direct sunlight.
- Keep out of reach of children.
FAQs:
1. What is TRILAVIR MINI Tablet used for?
TRILAVIR MINI Tablet is used for the treatment of HIV-1 infection in adults and adolescents. It is a combination of three antiretroviral drugs—Tenofovir disoproxil fumarate (TDF), Lamivudine (3TC), and Efavirenz (EFV)—that work together to reduce the viral load and prevent the progression of HIV to AIDS.It is commonly utilized in blend with other antiretroviral specialists.
2. What are the active ingredients in TRILAVIR MINI Tablet?
TRILAVIR MINI contains the following active ingredients:
- Tenofovir disoproxil fumarate (TDF) – 300 mg
- Lamivudine (3TC) – 150 mg
- Efavirenz (EFV) – 200 mg
These ingredients combine to inhibit HIV replication, thus helping to manage HIV infection.
3. How does TRILAVIR MINI Tablet work?
TRILAVIR MINI works by inhibiting the reverse transcriptase enzyme, which is essential for HIV replication.
- TDF and 3TC are nucleoside reverse transcriptase inhibitors (NRTIs) that block the viral replication process.
- EFV is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that targets the same enzyme but through a different mechanism.
- Together, these medications reduce the viral load and improve immune function in HIV-positive individuals.
4. How should I take TRILAVIR MINI Tablet?
- Take 1 TRILAVIR MINI tablet daily, as prescribed by your doctor.
- It can be taken with or without food.
- Take the tablet at the same time each day for consistency.
5. Can TRILAVIR MINI cure HIV?
No, TRILAVIR MINI does not cure HIV. It helps manage the infection by reducing the viral load and preventing the progression to AIDS, but lifelong treatment is required to control the virus.
6. What are the common side effects of TRILAVIR MINI Tablet?
Common side effects include:
- Nausea
- Dizziness
- Fatigue
- Headache
- Diarrhea
Serious side effects (rare) may include:
- Liver and kidney problems
- Severe skin reactions
- Central nervous system effects, such as mood changes or sleep disturbances, mainly due to Efavirenz.
7.Could I at any point quit taking TRILAVIR Smaller than normal assuming I feel significantly improved?
No, do not stop taking TRILAVIR MINI without consulting your healthcare provider. Stopping the medication can cause the virus to replicate again and may lead to drug resistance or a rebound in viral load.